Evaluation of technical urinary tract complications in kidney transplantation recipients with a prolonged dialysis history

Surgery. 2023 Aug;174(2):136-141. doi: 10.1016/j.surg.2023.02.013. Epub 2023 Apr 6.

Abstract

Background: The kidney transplant waiting list continues to expand, resulting in prolonged dialysis times exceeding 8 years before transplantation in some regions. The relationship between long-term dialysis and urinary tract complications after kidney transplant remains largely unexplored. This study aims to evaluate post-kidney transplant complications in patients with a history of prolonged dialysis.

Methods: A single-center, retrospective cohort study of patients maintained on dialysis ≥8 years before kidney transplant between January 2000 and July 2020 was conducted. Clinical variables, including demographics and comorbidities, were reviewed. The primary objective was the development of a technical urinary tract complication. Secondary outcomes included any postoperative complication by type, stratified by medical and surgical complications.

Results: Overall, 376 patients met the inclusion criteria. The mean pre-kidney transplant dialysis time was 10.2 ± 2.6 years. The majority (65.7%) of the study participants were anuric. Four patients (1.1%) experienced a urine leak, and 8 patients (2.1%) had a ureteral stricture. Any complication was observed in 111 (29.5%) patients, with urinary tract infections being the most common. Urinary catheters remained in place for a median of 4 (3, 5) days. Drains were commonly used (62.8%) for a median of 5 (4, 6) days.

Conclusion: In our large, single-center experience with kidney transplants in high-risk patients with prolonged dialysis and anuria, the technical urinary tract complications rate remained low. With the current literature consisting of small cohorts and having relatively short pre-kidney transplant dialysis periods, our analysis addresses the shortcomings of the literature while suggesting that this patient population may not truly be "high risk."

MeSH terms

  • Humans
  • Kidney Transplantation* / adverse effects
  • Kidney Transplantation* / methods
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Renal Dialysis / adverse effects
  • Retrospective Studies
  • Urinary Tract Infections* / epidemiology
  • Urinary Tract Infections* / etiology
  • Urinary Tract*