Contextualized medication event extraction with levitated markers

J Biomed Inform. 2023 May:141:104347. doi: 10.1016/j.jbi.2023.104347. Epub 2023 Apr 6.

Abstract

Automatic extraction of patient medication histories from free-text clinical notes can increase the amount of relevant information to clinicians for developing treatment plans. In addition to detecting medication events, clinical text mining systems must also be able to predict event context, such as negation, uncertainty, and time of occurrence, in order to construct accurate patient timelines. Towards this goal, we introduce Levitated Context Markers (LCMs), a novel transformer-based model for contextualized event extraction. LCMs are an adaptation of levitated markers -originally developed for relation extraction- that allow pretrained transformer models to utilize global input representations while also focusing on event-related subspans using a sparse attention mechanism. In addition to outperforming a strong baseline model on the Contextualized Medication Event Dataset, we show that LCMs' sparse attention can provide interpretable predictions by detecting relevant context cues in an unsupervised manner.

Keywords: Clinical NLP; Context classification; Event extraction; Levitated markers; Text mining.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Data Mining*
  • Humans
  • Natural Language Processing
  • Records*