The cell's dilemma: resolving directional decisions

Jonathan H Schrope; Anna Huttenlocher

doi:10.1016/j.it.2023.03.011

The cell's dilemma: resolving directional decisions

Trends Immunol. 2023 May;44(5):324-325. doi: 10.1016/j.it.2023.03.011. Epub 2023 Apr 6.

Authors

Jonathan H Schrope¹, Anna Huttenlocher²

Affiliations

¹ Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53705, USA.
² Department of Pediatrics and Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address: huttenlocher@wisc.edu.

Abstract

How neutrophils make decisions about polarity and migration path in complex tissue environments in situ remains unclear. Hadjitheodorou et al. describe how an internal mechanical regulator might help cells resolve the dilemma of two competing cell fronts.

The cell's dilemma: resolving directional decisions

Authors

Affiliations

Abstract

Publication types

MeSH terms

Grants and funding