Hierarchical Vaccine Allocation Based on Epidemiological and Behavioral Considerations

IEEE/ACM Trans Comput Biol Bioinform. 2023 Sep-Oct;20(5):2981-2991. doi: 10.1109/TCBB.2023.3265317. Epub 2023 Oct 9.

Abstract

Vaccines have proven useful in curbing contagion from new strains of the SARS-CoV-2 virus. However, equitable vaccine allocation continues to be a significant challenge worldwide, necessitating a comprehensive allocation strategy incorporating heterogeneity in epidemiological and behavioral considerations. In this paper, we present a hierarchical allocation strategy that assigns vaccines to zones and their constituent neighborhoods cost-effectively, based on their population density, susceptibility, infected count, and attitude towards vaccinations. Moreover, it includes a module that tackles vaccine shortages in certain zones by locally transferring vaccines from zones with surplus vaccines. We leverage the epidemiological, socio-demographic, and social media datasets from Chicago and Greece and their constituent community areas to show that the proposed allocation approach assigns vaccines based on the chosen criteria and captures the effects of disparate vaccine adoption rates. We conclude the paper with a lowdown on future efforts to extend this study to design models for effective public policies and vaccination strategies that curtail vaccine purchase costs.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Humans
  • SARS-CoV-2
  • Social Media*
  • Vaccines*

Substances

  • Vaccines