Lessons from Pasteur may help prevent the deadly relapse of Ebola in patients: Using contingency vaccination to avoid Ebola relapse in immune-privileged organs

Wei Ye; Chuantao Ye; Jia Li; Yingfeng Lei; Fanglin Zhang

doi:10.3389/fimmu.2023.1060481

Lessons from Pasteur may help prevent the deadly relapse of Ebola in patients: Using contingency vaccination to avoid Ebola relapse in immune-privileged organs

Front Immunol. 2023 Mar 20:14:1060481. doi: 10.3389/fimmu.2023.1060481. eCollection 2023.

Authors

Wei Ye¹, Chuantao Ye², Jia Li³, Yingfeng Lei¹, Fanglin Zhang¹

Affiliations

¹ Department of Microbiology, School of Preclinical Medicine, Airforce Medical University: Fourth Military Medical University, Xi'an, Shaanxi, China.
² Department of Infectious Diseases, Tangdu Hospital, Airforce Medical University: Fourth Military Medical University, Xi'an, Shaanxi, China.
³ Department of Neurology, Xi'an International Medical Center Hospital, Xi'an, Shaanxi, China.

No abstract available

Keywords: Ebola Virus Disease (EVD); Ebola virus (EBOV); Filovirus; contingency vaccination; immune-privileged organ; neutralizing antibody (NAb); vaccine; virus relapse.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Viral
Ebolavirus*
Hemorrhagic Fever, Ebola* / prevention & control
Humans
Vaccination

Substances

Antibodies, Viral

Grants and funding

This work was supported by the National Natural Science Foundation of China (82172272, 82072268, 81871697) and a university supporting grant (no. 2021JSTS10).