Epigenetics, genomics imprinting and non-coding RNAs

Gautham Manoj; Krishna Anjali; Anandhu Presannan; Nidheesh Melethadathil; Renuka Suravajhala; Prashanth Suravajhala

doi:10.1016/bs.pmbts.2023.02.001

Epigenetics, genomics imprinting and non-coding RNAs

Prog Mol Biol Transl Sci. 2023:197:93-104. doi: 10.1016/bs.pmbts.2023.02.001. Epub 2023 Mar 13.

Authors

Gautham Manoj¹, Krishna Anjali¹, Anandhu Presannan¹, Nidheesh Melethadathil¹, Renuka Suravajhala¹, Prashanth Suravajhala²

Affiliations

¹ Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Clappana, Kerala, India.
² Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Clappana, Kerala, India. Electronic address: prash@am.amrita.edu.

PMID: 37019598
DOI: 10.1016/bs.pmbts.2023.02.001

Abstract

Epigenetic traits are heritable phenotypes caused by alterations in chromosomes rather than DNA sequences. The actual epigenetic expression of the somatic cells of a species is identical, however, they may show distinct subtleties in various cell types in which they may be affected. Several recent studies demonstrated that the epigenetic system plays a very important role in regulating all biological natural processes in the body from birth to death. We outline the essential elements of epigenetics, genomic imprinting, and non-coding RNAs in this mini-review.

Keywords: Cellular differentiation; Epigenetics; Imprinting; Non-coding RNAs; lncRNAs; miRNAs.

Publication types

Review

MeSH terms

Epigenesis, Genetic
Genomic Imprinting*
Genomics
RNA, Long Noncoding* / genetics

Substances

RNA, Long Noncoding