Emerging Pathogenic Viral Infections of the Eye

Annu Rev Vis Sci. 2023 Sep 15:9:71-89. doi: 10.1146/annurev-vision-100820-010504. Epub 2023 Apr 5.

Abstract

Global health security threats and the public health impact resulting from emerging infectious diseases including the ongoing COVID-19 pandemic and recent Ebola virus disease outbreaks continuously emphasize the need for a comprehensive approach to preparedness, management of disease outbreaks, and health sequelae associated with emergent pathogens. A spectrum of associated ophthalmic manifestations, along with the potential persistence of emerging viral pathogens in ocular tissues, highlight the importance of an ophthalmic approach to contributing to efforts in the response to public health emergencies from disease outbreaks. This article summarizes the ophthalmic and systemic findings, epidemiology, and therapeutics for emerging viral pathogens identified by the World Health Organization as high-priority pathogens with epidemic potential.

Keywords: COVID-19; Ebola virus disease; emerging infectious disease; ophthalmic manifestations; uveitis; viral persistence.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19*
  • Eye
  • Face
  • Humans
  • Pandemics
  • Virus Diseases*