Where it all started

Long Zhang; Na Li; Ren Xu

doi:10.7554/eLife.87355

Where it all started

Elife. 2023 Apr 5:12:e87355. doi: 10.7554/eLife.87355.

Authors

Long Zhang¹, Na Li¹, Ren Xu²

Affiliations

¹ The First Affiliated Hospital of Xiamen University-ICMRS Collaborating Center for Skeletal Stem Cell, State Key Laboratory of Cellular Stress Biology, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.
² Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, China.

Abstract

The progenitor cells that form articular cartilage express a gene for a protein called NFATc1, which stops articular chondrocytes from developing too early in the joint.

Keywords: NFAT; articular cartilage; articular chondrocyte; differentiation; medicine; mouse; progenitors; regenerative medicine; stem cells; transcriptional factor.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Cartilage, Articular* / metabolism
Cell Differentiation / genetics
Chondrocytes* / metabolism
Stem Cells