Systematic comparison of experimental and human obstructive cholestasis reveals conservation of canonical pathway activation and biomarkers relevant for cholestatic liver disease

Genes Dis. 2022 Mar 14;10(1):18-21. doi: 10.1016/j.gendis.2022.02.003. eCollection 2023 Jan.

Eva Gijbels^{1

2}, Kevin De Muynck^{2

3}, Bart Vanderborght^{3

2}, Tim Meese^{4

5}, Filip Van Nieuwerburgh^{4

5}, Aude Vanlander⁶, Frederik Berrevoet⁶, Bart Hendrikx⁶, Anne Hoorens⁷, Hans Van Vlierberghe³, Mathieu Vinken¹, Lindsey Devisscher²

¹ Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
² Gut-Liver Immunopharmacology Unit, Basic and Applied Medical Sciences; Liver Research Centre Ghent; Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
³ Hepatology Research Unit, Internal Medicine and Paediatrics; Liver Research Centre Ghent; Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
⁴ Lab of Pharmaceutical Biotechnology, Ghent University, 9000 Ghent, Belgium.
⁵ NXTGNT, Ghent University, 9000 Ghent, Belgium.
⁶ Department of HPB Surgery and Liver Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.
⁷ Department of Pathology, Ghent University Hospital, 9000 Ghent, Belgium.

No abstract available