Efficacy of nondrug interventions in perinatal depression: A meta-analysis

Xiaoning Jiang; Hui Li; Denglan Wang; Ligang Shan; Fan Wang; Yimin Kang

doi:10.1016/j.psychres.2022.114916

Efficacy of nondrug interventions in perinatal depression: A meta-analysis

Psychiatry Res. 2022 Nov:317:114916. doi: 10.1016/j.psychres.2022.114916. Epub 2022 Oct 21.

Authors

Xiaoning Jiang¹, Hui Li², Denglan Wang³, Ligang Shan⁴, Fan Wang⁵, Yimin Kang⁶

Affiliations

¹ Medical Neurobiology Lab, Inner Mongolia Medical University, Huhhot 010110, China.
² Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing 100871, China.
³ Xinjiang Key Laboratory of Neurological Disorder Research, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830063, China.
⁴ Department of Anesthesiology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen 361021, China.
⁵ Beijing Hui-Long-Guan Hospital, Peking University, Beijing 100096, China. Electronic address: FanWang@bjmu.edu.cn.
⁶ Medical Neurobiology Lab, Inner Mongolia Medical University, Huhhot 010110, China. Electronic address: kangym@immu.edu.cn.

PMID: 37000462
DOI: 10.1016/j.psychres.2022.114916

Abstract

Perinatal depression causes significant harm to mothers and unborn infants. Nondrug intervention is a common and acceptable method for reducing perinatal depression in pregnant women; however, it lacks an evidence-based basis. This study aimed to evaluate the effectiveness of nondrug interventions, such as cognitive behavioral therapy (CBT), interpersonal psychotherapy (IPT), and yoga, in reducing perinatal depression. Randomized controlled trials (RCTs) of CBT, IPT, and yoga for improving perinatal depression were searched in the Cochrane Library, PubMed, Web of Science, Embase, ProQuest, ScienceDirect, ClinicalKey, Wanfang Data (Chinese database), and China Knowledge Resource Integrated Database. The retrieval time limit was set from the establishment of the database to December 2021. Twenty-one studies involving a total of 1981 participants were included.The present meta-analysis showed that CBT and IPT could effectively alleviate depressive symptoms in perinatal women, and the curative effect of IPT was better than that of CBT. There was no significant difference in the improvement effect of yoga on participants with depressive symptoms compared with that in the controls.This study was registered with the International Prospective Register of Systematic Reviews (PROSPERO, CRD42022307675).

Keywords: Cognitive behavioral therapy; Interpersonal psychotherapy; Meta-analysis; Nondrug; Perinatal depression; Yoga.

Publication types

Meta-Analysis
Review
Research Support, Non-U.S. Gov't

MeSH terms

Cognitive Behavioral Therapy* / methods
Depression / therapy
Depressive Disorder* / therapy
Female
Humans
Parturition
Pregnancy
Psychotherapy / methods
Systematic Reviews as Topic