Thiopurines are an independent risk factor for active tuberculosis in inflammatory bowel disease patients

World J Gastroenterol. 2023 Mar 7;29(9):1536-1538. doi: 10.3748/wjg.v29.i9.1536.

Authors

Flora Maria Lorenzo Fortes¹, Raquel Rocha², Genoile Oliveira Santana¹

Affiliations

¹ Ciências da Vida, Universidade do Estado da Bahia, Salvador 41150000, Brazil, and Programa de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador 40110060, Brazil.
² Ciência da Nutrição, Universidade Federal da Bahia, Salvador 40110160, Brazil. raquelrocha2@yahoo.com.br.

Abstract

The use of thiopurines is an independent risk factor for active tuberculosis in patients with inflammatory bowel disease.

Keywords: Inflammatory bowel disease; Risk; Therapy; Thiopurines; Tuberculosis.

©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

MeSH terms

Azathioprine
Humans
Immunosuppressive Agents / adverse effects
Inflammatory Bowel Diseases* / complications
Inflammatory Bowel Diseases* / drug therapy
Mercaptopurine / adverse effects
Purine Nucleosides
Risk Factors
Tuberculosis* / epidemiology

Substances

Azathioprine
Immunosuppressive Agents
Purine Nucleosides
Mercaptopurine