Applications of MXene and its modified materials in skin wound repair

Ziyan Zhang; Zhiping Qi; Weijian Kong; Renfeng Zhang; Chunli Yao

doi:10.3389/fbioe.2023.1154301

Applications of MXene and its modified materials in skin wound repair

Front Bioeng Biotechnol. 2023 Mar 13:11:1154301. doi: 10.3389/fbioe.2023.1154301. eCollection 2023.

Authors

Ziyan Zhang¹, Zhiping Qi¹, Weijian Kong², Renfeng Zhang², Chunli Yao³

Affiliations

¹ Department of Orthopedic Surgery, The Second Hospital of Jilin University, Changchun, China.
² The Second Hospital of Jilin University, Changchun, China.
³ Department of Dermatology, The Second Hospital of Jilin University, Changchun, China.

Abstract

The rapid healing and repair of skin wounds has been receiving much clinical attention. Covering the wound with wound dressing to promote wound healing is currently the main treatment for skin wound repair. However, the performance of wound dressing prepared by a single material is limited and cannot meet the requirements of complex conditions for wound healing. MXene is a new two-dimensional material with electrical conductivity, antibacterial and photothermal properties and other physical and biological properties, which has a wide range of applications in the field of biomedicine. Based on the pathophysiological process of wound healing and the properties of ideal wound dressing, this review will introduce the preparation and modification methods of MXene, systematically summarize and review the application status and mechanism of MXene in skin wound healing, and provide guidance for subsequent researchers to further apply MXene in the design of skin wound dressing.

Keywords: MXene; antibacterial; biocompatibility; conductivity; skin wound repair.

Publication types

Review

Grants and funding

This work was supported by National Natural Science Foundation of China (8200230). Health Special Project of Jilin Province (2020SCZT013). Science and Technology Proof of Concept Project of Jilin University (2022GN019). Natural Science Foundation of Jilin Provincial Science and Technology Department (20200201454JC) and Bethune Project of Jilin University (2022B43).