Mpox (Monkeypox) and the Eye: Ocular Manifestation, Diagnosis, Treatment and Vaccination

Viruses. 2023 Feb 23;15(3):616. doi: 10.3390/v15030616.

Abstract

At present, the world is at the tipping point of the outbreak of mpox. The World Health Organization has declared the current mpox outbreak a 'public health emergency of international concern'. Mpox has been shown to be associated with several ocular manifestations. Given the current state of the mpox outbreak, healthcare providers, particularly ophthalmologists, need to be aware of these ophthalmic symptoms and how to manage them. In this review, we highlight current knowledge on the ocular symptoms of mpox virus (MPXV) infections and how to detect them. In addition, we summarize the treatment strategies for these ocular manifestations of MPXV infections and outline the relationship between vaccination and the ocular symptoms of mpox.

Keywords: eye disease; literature review; monkeypox; mpox; virus.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Outbreaks / prevention & control
  • Eye
  • Health Personnel
  • Humans
  • Monkeypox virus
  • Mpox (monkeypox)* / diagnosis
  • Mpox (monkeypox)* / epidemiology
  • Mpox (monkeypox)* / prevention & control
  • Vaccination

Grants and funding

This work was supported by JSPS KAKENHI (grant no. JP 20K09824), a Grant on Rare and Intractable Diseases from the Ministry of Health, Labour, and Welfare of Japan (grant no. 22FC0201), and a Research Program on Emerging and Re-emerging Infectious Diseases grant from the Japan Agency for Medical Research and Development, AMED (grant no. JP21fk0108124j).