[Clinical effect of laparoscopy for the treatment of biliary stricture after biliary dilatation operation]

Zhonghua Wai Ke Za Zhi. 2023 Mar 29;61(5):375-380. doi: 10.3760/cma.j.cn112139-20221230-00554. Online ahead of print.
[Article in Chinese]

Abstract

Objective: To investigate the safety and effect of laparoscopy for the treatment of biliary stricture after the biliary dilatation operation. Methods: The clinical data of 78 patients,including 27 males and 51 females aged (48.6±14.2)years(range:17 to 76 years),who presented biliary stricture after biliary dilatation operation from January 2017 to June 2021 in the Department of Minimally Invasive Hepatobiliary Surgery,Hunan Provincial People's Hospital,were retrospectively collected,with 38 cases in the laparoscopy group and 40 cases in the laparotomy group. Of the 78 patients,there were 67 cases of cholangiojejunostomy stricture and 11 cases of stricture of the high intrahepatic bile duct. Statistical methods such as t-test and χ2 test were carried out to compare perioperative clinical data and follow-up information between the two groups. Results: Less intraoperative blood loss((102.6±76.4)ml vs. (162.5±105.9) ml, t=-2.874,P=0.005),shorter postoperative stay length of stay((10.5±3.7)days vs. (14.5±6.4)days, t=-3.379,P=0.001) and shorter waiting time for postoperative anal exhaust((2.0±0.6)days vs. (2.5±0.9)days, t=-2.827,P=0.006) were found in the laparoscopy group than that in the laparotomy group,with statistically significant differences. While there was no statistically difference in the operative time((252.8±54.7)minutes vs. (257.4±68.6)minutes,t=-0.331,P=0.742). Postoperative review and follow-up did not show statistically significant differences between the two groups in the residual stone rate(5.3%(2/38) vs. 5.0%(2/40)) and the incidence of recurrent biliary stricture(5.3%(2/38) vs. 7.5%(3/40))(both P>0.05). Conclusion: Laparoscopy may be safe and effective in the treatment of biliary stricture after the biliary dilatation operation,with less trauma,faster recovery compared to laparotomy.

目的: 探讨腹腔镜手术治疗胆管扩张症术后胆道狭窄的安全性和效果。 方法: 回顾性收集2017年1月至2021年6月在湖南省人民医院肝胆外科就诊的因胆管扩张症术后出现胆道狭窄的78例患者资料。男性27例,女性51例,年龄(48.6±14.2)岁(范围:17~76 岁),其中腹腔镜组38例,开放组40例。78例患者中,胆管空肠吻合口狭窄67例,肝内胆管高位狭窄11例。采用独立样本t检验、χ2检验等方法比较两组患者一般资料、围手术期数据和随访资料。 结果: 腹腔镜组患者术中出血量[(102.6±76.4)ml比(162.5±105.9)ml]、术后住院时间[(10.5±3.7)d比(14.5±6.4)d]、术后肛门排气时间[(2.0±0.6)d比(2.5±0.9)d]均优于开放组(t=-2.874,P=0.005;t=-3.379,P=0.001;t=-2.827,P=0.006)。而两组手术时间[(252.8±54.7)min比(257.4±68.6)min]的差异无统计学意义(t=-0.331,P=0.742)。通过术后复查及随访,两组结石残留率[5.3%(2/38)比5.0%(2/40)]和胆道再狭窄率[5.3%(2/38)比7.5%(3/40)]的差异无统计学意义(P值均>0.05)。 结论: 腹腔镜手术治疗胆管扩张症术后胆道狭窄较为安全、有效,与开放手术相比,具有创伤小、恢复快等优势。.

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