Heart Rate Recovery Assessed by Cardiopulmonary Exercise Testing in Patients with Cardiovascular Disease: Relationship with Prognosis

Int J Environ Res Public Health. 2023 Mar 7;20(6):4678. doi: 10.3390/ijerph20064678.

Abstract

Background: The use of exercise testing has expanded in recent decades and there is a wealth of information examining the prognostic significance of exercise variables, such as peak oxygen consumption or ventilatory measures whilst exercising. However, a paucity of research has investigated the use of recovery-derived parameters after exercise cessation. Heart rate recovery (HRR) has been considered a measure of the function of the autonomic nervous system and its dysfunction is associated with cardiovascular risk.

Objectives: We aim to provide an overview of the literature surrounding HRR and its prognostic significance in patients with cardiovascular disease undertaking an exercise test.

Data sources: In December 2020, searches of PubMed, Scopus, and ScienceDirect were performed using key search terms and Boolean operators.

Study selection: Articles were manually screened and selected as per the inclusion criteria.

Results: Nineteen articles met inclusion criteria and were reviewed. Disagreement exists in methodologies used for measuring and assessing HRR. However, HRR provides prognostic mortality information for use in clinical practice.

Conclusions: HRR is a simple, non-invasive measure which independently predicts mortality in patients with heart failure and coronary artery disease; HRR should be routinely incorporated into clinical exercise testing.

Keywords: coronary artery disease; exercise testing; heart failure; heart rate recovery; prognosis.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases*
  • Coronary Artery Disease*
  • Exercise Test / methods
  • Heart Failure*
  • Heart Rate / physiology
  • Humans

Grants and funding

This research received no external funding.