Immunosensors for Assay of Toxic Biological Warfare Agents

Biosensors (Basel). 2023 Mar 20;13(3):402. doi: 10.3390/bios13030402.

Abstract

An immunosensor for the assay of toxic biological warfare agents is a biosensor suitable for detecting hazardous substances such as aflatoxin, botulinum toxin, ricin, Shiga toxin, and others. The application of immunosensors is used in outdoor assays, point-of-care tests, as a spare method for more expensive devices, and even in the laboratory as a standard analytical method. Some immunosensors, such as automated flow-through analyzers or lateral flow tests, have been successfully commercialized as tools for toxins assay, but the research is ongoing. New devices are being developed, and the use of advanced materials and assay techniques make immunosensors highly competitive analytical devices in the field of toxic biological warfare agents assay. This review summarizes facts about current applications and new trends of immunosensors regarding recent papers in this area.

Keywords: Anthrax toxin; Shiga toxin; biosensor; botulinum toxin; cyanotoxin; immunoassay; ricin.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Warfare Agents*
  • Biosensing Techniques* / instrumentation
  • Biosensing Techniques* / methods
  • Humans
  • Immunoassay* / instrumentation
  • Immunoassay* / methods

Substances

  • Biological Warfare Agents