FDG PET/CT in a Case of Pure Ductal Adenocarcinoma of the Prostate With Osteolytic Metastases and Normal PSA Level

Clin Nucl Med. 2023 Jul 1;48(7):640-642. doi: 10.1097/RLU.0000000000004643. Epub 2023 Mar 26.

Abstract

Prostatic ductal adenocarcinoma is an uncommon aggressive subtype of prostate carcinoma. It is more likely to present with advanced stage and lower prostate-specific antigen. We describe FDG PET/CT findings in a case of pure prostatic ductal adenocarcinoma with lymph node, bone and lung metastases, normal serum prostate-specific antigen level, and elevated serum carbohydrate antigen 19-9 and carbohydrate antigen 724 levels. The primary tumor, and lymph node and bone metastases were hypermetabolic. All the bone metastases were osteolytic. The multiple lung metastases showed no significant FDG uptake, which may be due to small size.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / diagnostic imaging
  • Bone Neoplasms* / diagnostic imaging
  • Bone Neoplasms* / secondary
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms*
  • Male
  • Positron Emission Tomography Computed Tomography
  • Prostate / pathology
  • Prostate-Specific Antigen
  • Prostatic Neoplasms* / pathology
  • Radiopharmaceuticals

Substances

  • Prostate-Specific Antigen
  • Fluorodeoxyglucose F18
  • Radiopharmaceuticals