Cobalt catalyzed chemoselective reduction of nitroarenes: hydrosilylation under thermal and photochemical reaction conditions

Surajit Panda; Amareshwar Nanda; Rakesh R Behera; Rahul Ghosh; Bidraha Bagh

doi:10.1039/d3cc00328k

Cobalt catalyzed chemoselective reduction of nitroarenes: hydrosilylation under thermal and photochemical reaction conditions

Chem Commun (Camb). 2023 Apr 11;59(30):4527-4530. doi: 10.1039/d3cc00328k.

Authors

Surajit Panda¹, Amareshwar Nanda¹, Rakesh R Behera¹, Rahul Ghosh¹, Bidraha Bagh¹

Affiliation

¹ School of Chemical Sciences, National Institute of Science Education and Research (NISER), An OCC of Homi Bhabha National Institute, Bhubaneswar, Jatni, Khurda, Odisha, PIN 752050, India. bidraha@niser.ac.in.

PMID: 36975383
DOI: 10.1039/d3cc00328k

Abstract

Commercially available Co₂(CO)₈ was used as an effective catalyst for the hydrosilylation of nitroarenes under both thermal and photochemical conditions. A wide variety of nitroarenes with various functionalities were selectively reduced to aromatic amines. Syntheses of drug molecules expand the potential utility of this protocol. Experimental evidence suggested a radical pathway.