A Type II hybrid effectiveness-implementation study of an integrated CHW intervention to address maternal healthcare in rural Nepal

PLOS Glob Public Health. 2023 Jan 24;3(1):e0001512. doi: 10.1371/journal.pgph.0001512. eCollection 2023.

Abstract

Skilled care during pregnancy, childbirth, and postpartum is essential to prevent adverse maternal health outcomes, yet utilization of care remains low in many resource-limited countries, including Nepal. Community health workers (CHWs) can mitigate health system challenges and geographical barriers to achieving universal health coverage. Gaps remain, however, in understanding whether evidence-based interventions delivered by CHWs, closely aligned with WHO recommendations, are effective in Nepal's context. We conducted a type II hybrid effectiveness-implementation, mixed-methods study in two rural districts in Nepal to evaluate the effectiveness and the implementation of an evidence-based integrated maternal and child health intervention delivered by CHWs, using a mobile application. The intervention was implemented stepwise over four years (2014-2018), with 65 CHWs enrolling 30,785 families. We performed a mixed-effects Poisson regression to assess institutional birth rate (IBR) pre-and post-intervention. We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework to evaluate the implementation during and after the study completion. There was an average 30% increase in IBR post-intervention, adjusting for confounding variables (p<0.0001). Study enrollment showed 35% of families identified as dalit, janjati, or other castes. About 78-89% of postpartum women received at least one CHW-counseled home visit within 60 days of childbirth. Ten (53% of planned) municipalities adopted the intervention during the study period. Implementation fidelity, measured by median counseled home visits, improved with intervention time. The intervention was institutionalized beyond the study period and expanded to four additional hubs, albeit with adjustments in management and supervision. Mechanisms of intervention impact include increased knowledge, timely referrals, and longitudinal CHW interaction. Full-time, supervised, and trained CHWs delivering evidence-based integrated care appears to be effective in improving maternal healthcare in rural Nepal. This study contributes to the growing body of evidence on the role of community health workers in achieving universal health coverage.

Grants and funding

This work was supported by Grand Challenges Canada [GCC Grant Number 1808-17775 and TTS-2009-35989], United States Agency for International Development via a Partnerships for Enhanced Engagement in Research award [sponsor grant number AID-OAA-A11-00012, National Academy of Science subaward letter 2000007780] and the Office of the Director, National Institutes of Health under an Early Independence Award [DP5OD019894] to DM (the Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD) and the National Institute Of Dental & Craniofacial Research (NIDCR)). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Any findings, conclusions, or recommendations expressed in this article are those of the authors alone and do not necessarily reflect the views of the Grand Challenges Canada, United States Agency for International Development, National Institutes of Health or the National Academy of Science.