Nanosilver-functionalized polysaccharides as a platform for wound dressing

Environ Sci Pollut Res Int. 2023 Apr;30(19):54385-54406. doi: 10.1007/s11356-023-26450-2. Epub 2023 Mar 24.

Abstract

Polysaccharides that are naturally sourced have enormous promise as wound dressings, due to their wider availability and reasonable cost and good biocompatibility. Furthermore, nanosilver extensively applied in wound treatment is attributed to its broad spectrum of antimicrobial effects and lesser drug resistance. Consequently, wound dressings in corporating nanosilver have attracted wide-scale interest in wound healing, and nanosilver-functionalized polysaccharide-based wound dressings present an affordable option for healing of chronic wounds. This review encompasses preparation methods, classification, and antibacterial performances of nanosilver wound dressings. The prospective research arenas of nanosilver-based wound polysaccharide dressings are also elaborated. The review attempts to include a summary of the most recent advancements in silver nanotechnology as well as guidance for the investigation of nanosilver-functionalized polysaccharide-based wound dressings.

Keywords: Chitosan; Dextran; Hyaluronan; Polysaccharide; Silver nanoparticles; Wound dressings.

Publication types

  • Review

MeSH terms

  • Bandages*
  • Polysaccharides
  • Prospective Studies
  • Silver*

Substances

  • colloidal silver
  • Silver
  • Polysaccharides