Nanotechnologically Relevant Aspects of COVID-19 Vaccines

Ryan J Batley; Shaneel Chandra

doi:10.31083/j.fbe1501007

Nanotechnologically Relevant Aspects of COVID-19 Vaccines

Front Biosci (Elite Ed). 2023 Mar 8;15(1):7. doi: 10.31083/j.fbe1501007.

Authors

Ryan J Batley¹, Shaneel Chandra^{1

2}

Affiliations

¹ College of Science and Sustainability, School of Health, Medical and Applied Sciences, Central Queensland University, 4702 Rockhampton North, Queensland, Australia.
² Coastal Marine Ecosystems Research Centre, Central Queensland University, 4680 Gladstone, Queensland, Australia.

PMID: 36959106
DOI: 10.31083/j.fbe1501007

Abstract

The COVID-19 pandemic has affected several facets of human existence globally. To counter the spread of the virus, several vaccines have been developed and administered worldwide, using various technologies. Due to the need for the mRNA to be safely 'protected' until it can reach the host's cells, innovative transport, casing, stabilization and attachment mechanisms need to be harnessed to accompany the mRNA. Nanotechnology has featured in several such capacities. Therefore, our short review explores the role of nanomaterials in COVID vaccines, with a core focus on those based on mRNA. Often, the chemistry of these nanomaterials is critical to their success in these, and such important aspects are highlighted in our review. Towards the end, we have also discussed the various vaccine types.

Keywords: COVID; lipids; micro RNA; nanotechnology; vaccines.

Publication types

Review

MeSH terms

COVID-19 Vaccines
COVID-19* / prevention & control
Humans
Pandemics / prevention & control
RNA, Messenger
Vaccines*

Substances

COVID-19 Vaccines
RNA, Messenger
Vaccines