A Rare Case of Recurrent Immunotactoid Glomerulonephritis

Mohankumar Doraiswamy; Samir V Parikh; Sergey Brodsky

doi:10.7759/cureus.35136

A Rare Case of Recurrent Immunotactoid Glomerulonephritis

Cureus. 2023 Feb 18;15(2):e35136. doi: 10.7759/cureus.35136. eCollection 2023 Feb.

Authors

Mohankumar Doraiswamy^{1

2}, Samir V Parikh³, Sergey Brodsky⁴

Affiliations

¹ Department of Internal Medicine, Arkansas College of Osteopathic Medicine, Fort Smith, USA.
² Depatment of Internal Medicine, Mercy Health, Fort Smith, USA.
³ Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, USA.
⁴ Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, USA.

Abstract

Immunotactoid glomerulopathy is an uncommon cause of glomerular disease that results from deposits derived from immunoglobulins. This rare disease can occur in native kidneys and in transplant patients. They are present only in 0.5% to 1.4% of native kidney biopsies. Treatment of this disease is directed at the underlying monoclonal gammopathy, infection, and B-cell lymphoproliferative disorders. Prognosis is very guarded with 50% of people developing ESRD within five years of diagnosis. We present an interesting, rare case of recurrent immunotactoid glomerulonephritis which responded appropriately to rituximab therapy.

Keywords: general nephrology; general nephrology dialysis and transplanation; glomerular disease; glomerulonephritis; immunosuppression; immunotactoid; internal medicine. clinical nephrology; kidney biopsy; nephrology; nephrology disorders.

Publication types

Case Reports