Preparation of ultrasmall cyclodextrin nanogels by an inverse emulsion method using a cationic surfactant

Satomi Takeuchi; Andrea Cesari; Suzuka Soma; Yota Suzuki; Maria Antonietta Casulli; Kai Sato; Fabrizio Mancin; Takeshi Hashimoto; Takashi Hayashita

doi:10.1039/d3cc00523b

Preparation of ultrasmall cyclodextrin nanogels by an inverse emulsion method using a cationic surfactant

Chem Commun (Camb). 2023 Mar 30;59(27):4071-4074. doi: 10.1039/d3cc00523b.

Authors

Satomi Takeuchi¹, Andrea Cesari², Suzuka Soma¹, Yota Suzuki¹, Maria Antonietta Casulli¹, Kai Sato¹, Fabrizio Mancin², Takeshi Hashimoto¹, Takashi Hayashita¹

Affiliations

¹ Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1, Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan. ta-hayas@sophia.ac.jp.
² Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy.

PMID: 36938636
DOI: 10.1039/d3cc00523b

Abstract

Stable water-in-oil emulsion membranes can be prepared using [dilauryl(dimethyl)ammonium] bromide (DDAB), a cationic surfactant. We prepared ultrasmall cyclodextrin (γ-CyD) nanogels (γ-CyDngs) by forming ionic pairs between the secondary hydroxyl groups of γ-CyDs and DDAB. Fluorescence and NMR characterisation of the obtained γ-CyDngs revealed superior inclusion affinities compared with native γ-CyDs, beneficial for the solubilisation of hydrophobic compounds in water.