Cerebral infarction as initial manifestation of meningovascular neurosyphilis in an immunocompetent patient - A case report with long term follow-up

Davor Batinić; Ronald Antulov; Inge Klupka-Sarić; Anita Ivanković; Renata Jurina; Marijana Karlović Vidaković; Ivana Talić Drlje; Jurica Arapović

doi:10.1002/ccr3.7021

Cerebral infarction as initial manifestation of meningovascular neurosyphilis in an immunocompetent patient - A case report with long term follow-up

Clin Case Rep. 2023 Mar 15;11(3):e7021. doi: 10.1002/ccr3.7021. eCollection 2023 Mar.

Authors

Davor Batinić^{1

2}, Ronald Antulov^{3

4}, Inge Klupka-Sarić^{1

2}, Anita Ivanković^{1

2}, Renata Jurina^{1

2}, Marijana Karlović Vidaković⁵, Ivana Talić Drlje^{2

6}, Jurica Arapović^{2

7}

Affiliations

¹ Department of Neurology University Clinical Hospital Mostar Mostar Bosnia and Herzegovina.
² Faculty of Medicine University of Mostar Mostar Bosnia and Herzegovina.
³ Department of Radiology and Nuclear Medicine Hospital South West Jutland Esbjerg Denmark.
⁴ Department of Regional Health Research University of Southern Denmark Esbjerg Denmark.
⁵ Department of Radiology Polyclinic Medicol Split Croatia.
⁶ Department of Transfusion Medicine University Clinical Hospital Mostar Mostar Bosnia and Herzegovina.
⁷ Department of Infectious Diseases University Clinical Hospital Mostar Mostar Bosnia and Herzegovina.

Abstract

To present a 29-year-old immunocompetent patient with neurosyphilitic changes characterized by multiple acute ischemic brain strokes along with significant narrowing of several large intracranial arteries. Ceftriaxone treatment for 14 days followed by benzathine benzylpenicillin weekly for additional 3 weeks, showed improvement in meningovascular changes.

Keywords: magnetic resonance imaging; neurosyphilis; stroke; syphilitic arteritis.

Publication types

Case Reports