A ternary deep eutectic solvent-modified magnetic mixed iron hydroxide@MIL-101(Cr)-NH2 composite as a sorbent in magnetic solid phase extraction of organochlorine pesticides prior to GC-MS

Preeyaporn Phosiri; Prachathipat Pongpinyo; Yanawath Santaladchaiyakit; Rodjana Burakham

doi:10.1039/d2ra07704c

A ternary deep eutectic solvent-modified magnetic mixed iron hydroxide@MIL-101(Cr)-NH₂ composite as a sorbent in magnetic solid phase extraction of organochlorine pesticides prior to GC-MS

RSC Adv. 2023 Mar 16;13(13):8863-8872. doi: 10.1039/d2ra07704c. eCollection 2023 Mar 14.

Authors

Preeyaporn Phosiri¹, Prachathipat Pongpinyo², Yanawath Santaladchaiyakit³, Rodjana Burakham¹

Affiliations

¹ Materials Chemistry Research Center, Department of Chemistry, Faculty of Science, Khon Kaen University Khon Kaen 40002 Thailand rodjbu@kku.ac.th +66 4320 2373 +66 4300 9700 ext. 42174.
² Agricultural Production Sciences Research and Development Office, Department of Agriculture Bangkok 10900 Thailand.
³ Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan, Khon Kaen Campus Khon Kaen 40000 Thailand.

Abstract

A green solvent of ternary deep eutectic solvent (menthol-thymol-dodecanoic acid) was prepared and used as a functional reagent to modify a magnetic mixed iron hydroxide@MIL-101(Cr)-NH₂ composite. The proposed sorbent (MIH@MIL-101(Cr)-NH₂-TDES) was applied in magnetic solid phase extraction (MSPE) for the enrichment of organochlorine pesticides. The analytes were quantitively analyzed by GC-MS. The relationships of experimental parameters for preparing the proposed sorbent and the MSPE method were studied through a Box-Behnken design and a central composite design, respectively. Their optimized conditions were investigated using response surface methodology. Application of the MIH@MIL-101(Cr)-NH₂-TDES sorbent in MSPE successfully enhanced the sensitivity of GC-MS analysis, giving enrichment factors in the range of 56-168. The MSPE/GC-MS method was developed using MIH@MIL-101(Cr)-NH₂-TDES as a sorbent and was successfully employed for the preconcentration/determination of organochlorine residues in honey and tea samples. The satisfactory detection limits were in the ranges of 0.07-0.80 ng g^-1 and 0.7-8.5 ng g^-1 for honey and tea samples, respectively. Acceptable recoveries were obtained in the ranges of 81.7-107.3% and 85.4-109.3% for the spiked honey and tea samples, respectively, with RSDs lower than 10.0%.