Carbon Quantum Dots as Multi-Purpose Nanomaterial in Stem Cell Therapy

Chem Biodivers. 2023 Apr;20(4):e202200721. doi: 10.1002/cbdv.202200721. Epub 2023 Mar 23.

Abstract

Some issues, such as their obscure fate or low survival rate into the body during stem cell therapy, should be addressed to boost efficiency. Nanotechnology offers a suitable solution to combat such limitations. Carbon quantum dots (CQDs) are carbon-based nanomaterials and may be used as multi-purpose compounds in stem cell therapy. CQDs are excellent choices for stem cell labeling thanks to their special features such as optical properties and good biocompatibility. Besides, they can modulate the biological function of stem cells, such as their proliferation, homing ability, and differentiation properties. Considering the charismatic feature of CQDs and their broad unique effect on stem cells, the current review aims to summarize the advancements in this field. Hence, we first focused on CQDs synthesis and their applications. In the next section, the stem cell categories will be discussed, and the final part is dedicated to the recent research evaluating the impact of CQDs on stem cell therapy.

Keywords: carbon; quantum dot; stem cell; tracking; translational medicine.

Publication types

  • Review

MeSH terms

  • Carbon
  • Cell- and Tissue-Based Therapy
  • Quantum Dots*

Substances

  • Carbon