Multiple system atrophy

Pract Neurol. 2023 Jun;23(3):208-221. doi: 10.1136/pn-2020-002797. Epub 2023 Mar 16.

Abstract

This is a practical guide to diagnosing and managing multiple system atrophy (MSA). We explain the newly published Movement Disorders Society Consensus Diagnostic Criteria, which include new 'Clinically Established MSA' and 'Possible Prodromal MSA' categories, hopefully reducing time to diagnosis. We then highlight the key clinical features of MSA to aid diagnosis. We include a list of MSA mimics with suggested methods of differentiation from MSA. Lastly, we discuss practical symptom management in people living with MSA, including balancing side effects, with the ultimate aim of improving quality of life.

Keywords: CEREBELLAR DEGENERATION; CLINICAL NEUROLOGY; MOVEMENT DISORDERS; MULTISYSTEM ATROPHY.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Multiple System Atrophy* / diagnosis
  • Multiple System Atrophy* / therapy
  • Quality of Life