Hhip hits the brakes on lung tissue resident lymphocytes

Justinn Barr; Xin Sun

doi:10.1016/j.immuni.2023.02.008

Hhip hits the brakes on lung tissue resident lymphocytes

Immunity. 2023 Mar 14;56(3):465-467. doi: 10.1016/j.immuni.2023.02.008.

Authors

Justinn Barr¹, Xin Sun²

Affiliations

¹ Department of Pediatrics, University of California San Diego, La Jolla, CA.
² Department of Pediatrics, University of California San Diego, La Jolla, CA; Divison of Biological Sciences, University of California San Diego, La Jolla, CA. Electronic address: xinsun@health.ucsd.edu.

PMID: 36921570
DOI: 10.1016/j.immuni.2023.02.008

Abstract

Tissue-immune cell interactions in the periphery are well appreciated but incompletely understood. In this issue of Immunity, Wang et al. demonstrate how the disruption of a lung stromal niche leads to expansion of lung-resident lymphocytes and IFN-γ-driven exacerbation of emphysema.

Publication types

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MeSH terms

Lung*
Lymphocytes*