Facial nerve in skullbase tumors: imaging and clinical relevance

Eur J Med Res. 2023 Mar 14;28(1):121. doi: 10.1186/s40001-023-01078-7.

Abstract

Facial nerve, the 7th cranial nerve, is a mixed nerve composed of sensory and motor fibers, and its main branch is situated in the cerebellopontine angle. Facial nerve dysfunction is a debilitating phenomenon that can occur in skullbase tumors and Bell's pals. Recovery of the facial nerve dysfunction after surgery for skullbase tumors can be disappointing, but is usually favorable in Bell's palsy. Advances in magnetic resonance imaging (MRI) allow to visualize the facial nerve and its course in the cerebellopontine angle, also when a large tumor is present and compresses the nerve. Here, we describe the anatomical, neurochemical and clinical aspects of the facial nerve and highlight the recent progress in visualizing the facial nerve with MRI.

Keywords: Anatomy; Facial nerve; Histology; MR imaging; Skullbase tumors; Vestibular schwannoma.

Publication types

  • Review

MeSH terms

  • Clinical Relevance
  • Facial Nerve / diagnostic imaging
  • Facial Paralysis* / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasms*