Abstract
Despite the well documented increased risk of osteopenia in patients with breast cancer during chemotherapy and endocrine therapy, spontaneous cerebrospinal fluid rhinorrhea (CSFR) is still rare. The authors present a case of spontaneous CSFR that occurred during chemotherapy and endocrine therapy for breast cancer. The patient underwent a repair using myofascia and adipose tissue and was started on mannitol. There was no recurrence at 1-year follow-up. Therefore, clinicians should pay attention to the possibility of CSFR in patients with breast cancer, to avoid misdiagnosis.
Copyright © 2023 by Mutaz B. Habal, MD.
MeSH terms
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Antineoplastic Agents, Hormonal* / adverse effects
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Antineoplastic Agents, Hormonal* / therapeutic use
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Bone Density* / drug effects
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Breast Neoplasms* / drug therapy
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Cerebrospinal Fluid Rhinorrhea* / chemically induced
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Cerebrospinal Fluid Rhinorrhea* / diagnosis
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Cerebrospinal Fluid Rhinorrhea* / surgery
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Estrogen Antagonists* / adverse effects
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Estrogen Antagonists* / therapeutic use
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Female
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Humans
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Middle Aged
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Sphenoid Sinus / diagnostic imaging
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Sphenoid Sinus / pathology
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Tamoxifen* / adverse effects
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Tamoxifen* / therapeutic use
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Tomography, X-Ray Computed
Substances
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Tamoxifen
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Estrogen Antagonists
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Antineoplastic Agents, Hormonal