Two new linear peptides from the marine-derived fungus Penicillium sp. SCSIO 41512

Fei-Hua Yao; Xiao Liang; Shu-Hua Qi

doi:10.1080/10286020.2023.2189107

Two new linear peptides from the marine-derived fungus Penicillium sp. SCSIO 41512

J Asian Nat Prod Res. 2023 Oct;25(10):941-948. doi: 10.1080/10286020.2023.2189107. Epub 2023 Mar 14.

Authors

Fei-Hua Yao^{1

2}, Xiao Liang¹, Shu-Hua Qi^{1

3}

Affiliations

¹ CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
² University of Chinese Academy of Sciences, Beijing 100049, China.
³ Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China.

PMID: 36916424
DOI: 10.1080/10286020.2023.2189107

Abstract

Two new linear peptides, penicamides A and B (1 and 2), together with four known analogous were isolated from the extracts of the marine-derived fungus Penicillium sp. SCSIO 41512. Their structures were elucidated by analysis of 1D/2D NMR data and HRESI-MS. Their absolute configurations were established by Marfey's methods and quantum chemical calculations.

Keywords: Marine-derived fungus; Penicillium sp; linear peptide.

MeSH terms

Fungi / chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Penicillium* / chemistry
Peptides

Substances

Peptides