15,15-Diphenyl-2,3,4,5,6,8,9,11,12-octa-hydro-imidazo[2,1- h][1,4,12]trioxa[7]thia-[9]azacyclo-tetra-decin-14(15 H)-one

Walid Guerrab; Abderrazzak El Moutaouakil Ala Allah; Abdulsalam Alsubari; Joel T Mague; Youssef Ramli

doi:10.1107/S2414314623001256

15,15-Diphenyl-2,3,4,5,6,8,9,11,12-octa-hydro-imidazo[2,1- h][1,4,12]trioxa[7]thia-[9]azacyclo-tetra-decin-14(15 H)-one

IUCrdata. 2023 Feb 17;8(Pt 2):x230125. doi: 10.1107/S2414314623001256. eCollection 2023 Feb.

Authors

Walid Guerrab¹, Abderrazzak El Moutaouakil Ala Allah¹, Abdulsalam Alsubari², Joel T Mague³, Youssef Ramli¹

Affiliations

¹ Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
² Laboratory of Medicinal Chemistry, Faculty of Clinical Pharmacy, 21 September University, Yemen.
³ Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.

Abstract

The title mol-ecule, C₂₃H₂₆N₂O₄S, adopts a cup-shaped conformation. In the crystal, layers lying parallel to the ab plane are formed by C-H⋯O hydrogen bonds and C-H⋯π(ring) inter-actions. The layers stack along the c-axis direction through normal van der Waals inter-actions.

Keywords: crown ether; crystal structure; thiohydantoin.

Grants and funding

JTM thanks Tulane University for support of the Tulane Crystallography Laboratory.