Commercially Available Textiles as a Scaffolding Platform for Large-Scale Cell Culture

Tarun Agarwal; Sheri-Ann Tan; Shanmuga Sharan Rathnam Vuppaladadium; Tanmayi Sajja; Tapas Kumar Maiti

doi:10.1155/2023/2227509

Commercially Available Textiles as a Scaffolding Platform for Large-Scale Cell Culture

Int J Biomater. 2023 Mar 1:2023:2227509. doi: 10.1155/2023/2227509. eCollection 2023.

Authors

Tarun Agarwal^{1

2}, Sheri-Ann Tan³, Shanmuga Sharan Rathnam Vuppaladadium⁴, Tanmayi Sajja², Tapas Kumar Maiti¹

Affiliations

¹ Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal-721302, India.
² Department of Bio-Technology, Koneru Lakshmaiah Education Foundation, Vaddeswaram, AP, India.
³ Department of Bioscience, Faculty of Applied Sciences, Tunku Abdul Rahman University of Management and Technology, Kuala Lumpur 53300, Malaysia.
⁴ Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, India.

Abstract

The present study outlines the evaluation of textile materials that are currently in the market for cell culture applications. By using normal LaserJet printing techniques, we created the substrates, which were then characterized physicochemically and biologically. In particular, (i) we found that the weave pattern and (ii) the chemical nature of the textiles significantly influenced the behaviour of the cells. Textiles with closely knitted fibers and cell adhesion motifs, exhibited better cell adhesion and proliferation over a period of 7 days. All the substrates supported good viability of cells (>80%). We believe that these aspects make commercially available textiles as a potential candidate for large-scale culture of adherent cells.