Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience

Xiaoyang Lu; Yuansheng Zhang; Hu Zhou; Lipeng Jian; Shi Yin; Tao Li; Wei Huang

doi:10.3389/fneur.2023.1050619

Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience

Front Neurol. 2023 Feb 22:14:1050619. doi: 10.3389/fneur.2023.1050619. eCollection 2023.

Authors

Xiaoyang Lu¹, Yuansheng Zhang², Hu Zhou¹, Lipeng Jian², Shi Yin², Tao Li¹, Wei Huang¹

Affiliations

¹ Department of Neurosurgery, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
² The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.

Abstract

Objective: To evaluate the efficacy and safety of flow diverters (FD) in the treatment of vertebral artery dissecting aneurysm (VADA).

Methods: A total of 16 patients with 17 unruptured VADAs treated with FD from January 2017 to May 2021 were included. Data of clinical outcomes and radiographic examination were collected and assessed by the modified Rankin Scale (mRS) and O'Kelly-Marotta (OKM) grading scale.

Results: All patients were treated with a single FD. No perioperative complications occurred. The mean age was 55.1 years old. The mean size of the aneurysm was 10.4 mm. All patients had a favorable occlusion (OKM D + C3) result and the complete occlusion rate in the 6th month was 66.7% (OKM D). The mean clinical follow-up time was 7.8 months, and all patients had a good clinical outcome (mRS = 0). No procedure-related complication occurred at the last follow-up time.

Conclusion: FD is an effective and safe tool for treating unruptured VADA. Long-term prospective studies with a large sample are still needed to confirm these findings in the future.

Keywords: aneurysm; embolization; endovascular treatment; flow diverter; vertebral artery dissection.

Grants and funding

This work was funded by the National Natural Science Foundation of China (Grant No. 82001278), the Fund for Young Doctors with the First People's Hospital of Yunnan Province (Grant No. KHBS-2020-014), Yunnan Fundamental Research Projects (Grant No. 202101AU070106), and Joint Projects of Yunnan Provincial Science and Technology Department and Kunming Medical University for Applied Basic Research (Grant No. 202101AY070001-252).