Laser Interstitial Thermal Therapy for Epilepsy

Jamie J Van Gompel; David B Burkholder; Jonathon J Parker; Sangeet S Grewal; Erik H Middlebrooks; Vance T Lehman; Kai J Miller; Eva C Alden; Timothy J Kaufmann

doi:10.1016/j.nec.2022.11.005

Laser Interstitial Thermal Therapy for Epilepsy

Neurosurg Clin N Am. 2023 Apr;34(2):247-257. doi: 10.1016/j.nec.2022.11.005. Epub 2023 Jan 30.

Authors

Jamie J Van Gompel¹, David B Burkholder², Jonathon J Parker³, Sangeet S Grewal⁴, Erik H Middlebrooks⁵, Vance T Lehman⁶, Kai J Miller⁷, Eva C Alden⁸, Timothy J Kaufmann⁶

Affiliations

¹ Department of Neurosurgery Mayo Clinic, 200 First street, SouthWest, Rochester, MN 55905, USA. Electronic address: Vangompel.jamie@mayo.edu.
² Department of Neurology, Division of epilepsy, Mayo Clinic, 200 First street, SouthWest, Rochester, MN 55905, USA.
³ Department of Neurosurgery Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA.
⁴ Department of Neurosurgery Mayo Clinic, 4500 San Pablo Road S Building 3-310, Jacksonville, FL 32224, USA.
⁵ Department of Radiology Mayo Clinic, 4500 San Pablo Road S Building 3-310, Jacksonville, FL 32224.
⁶ Department of Radiology Mayo Clinic, 200 First street, SouthWest, Rochester, MN 55905, USA.
⁷ Department of Neurosurgery Mayo Clinic, 200 First street, SouthWest, Rochester, MN 55905, USA.
⁸ Department of Psychiatry Mayo Clinic, 200 First street, SouthWest, Rochester, MN 55905, USA.

PMID: 36906331
DOI: 10.1016/j.nec.2022.11.005

Abstract

Laser interstitial thermal therapy is an important new technique with a diverse use in epilepsy. This article gives an up-to-date evaluation of the current use of the technique within epilepsy, as well as provides some guidance to novice users appropriate clinical cases for its use.

Keywords: Epilepsy; Laser interstitial thermal therapy (LITT); Minimally invasive.

Publication types

Review

MeSH terms

Epilepsy* / surgery
Humans
Hyperthermia, Induced* / methods
Laser Therapy* / methods
Lasers
Magnetic Resonance Imaging / methods