Posterior Fossa Laser Interstitial Thermal Therapy in Children

Giuseppe Mirone; Domenico Cicala; Giuseppe Cinalli

doi:10.1016/j.nec.2022.11.002

Posterior Fossa Laser Interstitial Thermal Therapy in Children

Neurosurg Clin N Am. 2023 Apr;34(2):227-237. doi: 10.1016/j.nec.2022.11.002. Epub 2023 Jan 30.

Authors

Giuseppe Mirone¹, Domenico Cicala¹, Giuseppe Cinalli²

Affiliations

¹ Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, AORN, Via Mario Fiore 6 80121, Napoli, Italy.
² Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, AORN, Via Mario Fiore 6 80121, Napoli, Italy. Electronic address: giuseppe.cinalli@gmail.com.

PMID: 36906329
DOI: 10.1016/j.nec.2022.11.002

Abstract

Real-time, MRI-guided laser interstitial thermal therapy (MRgLITT) is emerging as a minimally invasive technique for epilepsy surgery and for deep-seated tumors in the pediatric population. However, MRgLITT for posterior fossa lesions poses a unique challenge that is especially evident in this age range and remains understudied. In this study, we report our experience and analyze the current literature on MRgLITT for the treatment of posterior fossa in children.

Keywords: Brainstem; Cavernous malformation; Laser interstitial thermal therapy; Magnetic resonance imaging; Minimally invasive; Pediatric tumor; Posterior fossa; Tumor ablation.

Publication types

Review

MeSH terms

Child
Epilepsy* / surgery
Humans
Laser Therapy* / methods
Lasers
Magnetic Resonance Imaging / methods
Stereotaxic Techniques
Surgery, Computer-Assisted* / methods
Treatment Outcome