Association between Serum Vitamin D and Metabolic Syndrome in a Sample of Adults in Lebanon

Nutrients. 2023 Feb 23;15(5):1129. doi: 10.3390/nu15051129.

Abstract

The evidence on the association between vitamin D and metabolic syndrome (MetS) is inconclusive. This was a cross-sectional study to explore the relationship between vitamin D serum levels and MetS in a sample of Lebanese adults (n = 230), free of diseases that affect vitamin D metabolism, recruited from an urban large university and neighboring community. MetS was diagnosed according to the International Diabetes Federation criteria. A logistic regression analysis was performed taking MetS as the dependent variable, and vitamin D was forced into the model as an independent variable. The covariates included sociodemographic, dietary, and lifestyle variables. The mean (SD) serum vitamin D was 17.53 (12.40) ng/mL, and the prevalence of MetS was 44.3%. Serum vitamin D was not associated with MetS (OR = 0.99 (95% CI: 0.96, 1.02), p < 0.757), whereas the male sex, compared with the female sex and older age, was associated with higher odds of having MetS (OR = 5.92 (95% CI: 2.44, 14.33), p < 0.001 and OR = 1.08 (95% CI: 1.04, 1.11), p < 0.001, respectively). This result adds to the controversy in this field. Future interventional studies are warranted to better understand the relationship between vitamin D and MetS and metabolic abnormalities.

Keywords: Lebanon; adults; metabolic syndrome; vitamin D.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Humans
  • Lebanon
  • Male
  • Metabolic Syndrome* / epidemiology
  • Prevalence
  • Risk Factors
  • Vitamin D
  • Vitamins

Substances

  • Vitamin D
  • Vitamins

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