Self-powered photoelectrochemical aptasensor based on hollow tubular g-C3N4/Bi/BiVO4 for tobramycin detection

Yuanyuan Zhang; Yuan Zhu; Tianjing Zeng; Lu Qiao; Mingjuan Zhang; Kexin Song; Nian Yin; Yani Tao; Yue Zhao; Chang Zhang; Yi Zhang

doi:10.1016/j.aca.2023.340951

Self-powered photoelectrochemical aptasensor based on hollow tubular g-C₃N₄/Bi/BiVO₄ for tobramycin detection

Anal Chim Acta. 2023 Apr 15:1250:340951. doi: 10.1016/j.aca.2023.340951. Epub 2023 Feb 10.

Authors

Yuanyuan Zhang¹, Yuan Zhu¹, Tianjing Zeng², Lu Qiao¹, Mingjuan Zhang¹, Kexin Song¹, Nian Yin¹, Yani Tao¹, Yue Zhao¹, Chang Zhang³, Yi Zhang⁴

Affiliations

¹ College of Environmental Science and Engineering, Hunan University, Changsha, Hunan, 410082, China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, Hunan, 410082, China.
² Hunan Ecological and Environmental Monitoring Center, Changsha, Hunan, 410001, China.
³ College of Environmental Science and Engineering, Hunan University, Changsha, Hunan, 410082, China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, Hunan, 410082, China. Electronic address: zhangchang@hnu.edu.cn.
⁴ College of Environmental Science and Engineering, Hunan University, Changsha, Hunan, 410082, China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, Hunan, 410082, China. Electronic address: zyi@hnu.edu.cn.

PMID: 36898823
DOI: 10.1016/j.aca.2023.340951

Abstract

A highly sensitive photoelectrochemical aptasensor based on phosphorus-doped hollow tubular g-C₃N₄/Bi/BiVO₄ (PT-C₃N₄/Bi/BiVO₄) for tobramycin (TOB) detecting was developed. This aptasensor is a self-powered sensing system which could generate the electrical output under visible light irradiation with no external voltage supply. Based on the surface plasmon resonance (SPR) effect and unique hollow tubular structure of PT-C₃N₄/Bi/BiVO₄, the PEC aptasensor exhibited an enhanced photocurrent and favorably specific response to TOB. Under the optimized conditions, the sensitive aptasensor presented a wider linearity to TOB in the range of 0.01-50 ng mL^-1 with a low detection limit of 4.27 pg mL^-1. This sensor also displayed a satisfying photoelectrochemical performance with optimistic selectivity and stability. In addition, the proposed aptasensor was successfully applied to the detection of TOB in river water and milk samples.

Keywords: Bi/BiVO(4); Hollow tubular g-C(3)N(4); Photoelectrochemical biosensor; Self-powered platform; Tobramycin.

MeSH terms

Aptamers, Nucleotide* / chemistry
Biosensing Techniques*
Electrochemical Techniques
Light
Limit of Detection
Surface Plasmon Resonance
Tobramycin

Substances

Tobramycin
Aptamers, Nucleotide