Transfusion Strategies in the 21st Century: A Case-Based Narrative Report

Jennifer Shenker; Hiba Abuelhija; Oliver Karam; Marianne Nellis

doi:10.1016/j.ccc.2022.09.005

Transfusion Strategies in the 21st Century: A Case-Based Narrative Report

Crit Care Clin. 2023 Apr;39(2):287-298. doi: 10.1016/j.ccc.2022.09.005. Epub 2022 Nov 2.

Authors

Jennifer Shenker¹, Hiba Abuelhija², Oliver Karam³, Marianne Nellis⁴

Affiliations

¹ Department of Pediatrics, New York Presbyterian Hospital - Weill Cornell Medicine, 525 East 68th Street, M508, New York, NY 10065, USA.
² Pediatric Critical Care, Hadassah University Medical Center, Hadassah Ein Kerem, POB 12000, Jerusalem 911200, Israel.
³ Department of Pediatrics, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
⁴ Department of Pediatrics, Division of Pediatric Critical Care Medicine, Weill Cornell Medicine, 525 East 68th Street, M512, New York, NY 10065, USA. Electronic address: man9026@med.cornell.edu.

PMID: 36898774
DOI: 10.1016/j.ccc.2022.09.005

Abstract

The transfusion of all blood components (red blood cells, plasma, and platelets) has been associated with increased morbidity and mortality in children. It is essential that pediatric providers weigh the risks and benefits before transfusing a critically ill child. A growing body of evidence has demonstrated the safety of restrictive transfusion practices in critically ill children.

Keywords: Children; Critical illness; Transfusion.

Publication types

Review

MeSH terms

Blood Transfusion
Child
Critical Care
Critical Illness*
Erythrocyte Transfusion*
Humans