Profile of Cardiac Involvement in Children After Exposure to COVID-19

Indian Pediatr. 2023 May 15;60(5):385-388. doi: 10.1007/s13312-023-2886-1. Epub 2023 Mar 10.

Abstract

Objective: To evaluate the incidence and pattern of cardiac involvement in children post-COVID (coronavirus disease) infection in a tertiary care referral hospital in India.

Methods: A prospective observational study was conducted including all consecutive children with suspected MIS-C referred to the cardiology services.

Results: Of the 111 children with mean (SD) age was 3.5 (3.6) years, 95.4% had cardiac involvement. Abnormalities detected were coronary vasculopathy, pericardial effusion, valvular regurgitation, ventricular dysfunction, diastolic flow reversal in aorta, pulmonary hypertension, bradycardia and intra-cardiac thrombus. The survival rate post treatment was 99%. Early and short-term follow-up data was available in 95% and 70%, respectively. Cardiac parameters improved in majority.

Conclusion: Cardiac involvement post COVID-19 is often a silent entity and may be missed unless specifically evaluated for. Early echocardiography aided prompt diagnosis, triaging, and treatment, and helps in favorable outcomes.

Publication types

  • Observational Study

MeSH terms

  • COVID-19* / complications
  • COVID-19* / epidemiology
  • Child
  • Child, Preschool
  • Coronavirus Infections* / therapy
  • Echocardiography
  • Humans
  • Pericardial Effusion* / epidemiology
  • Pericardial Effusion* / etiology

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related