Determinants of blood glucose concentrations following a high carbohydrate meal in type 2 diabetes: A multiple linear regression analysis

Diabetes Res Clin Pract. 2023 Apr:198:110606. doi: 10.1016/j.diabres.2023.110606. Epub 2023 Mar 7.

Abstract

This study showed that in relatively well-controlled type 2 diabetes blood glucose levels after a high carbohydrate meal were associated positively with fasting blood glucose, but also positively with gastric emptying in the first hour and negatively with the increments in plasma glucagon-like peptide-1 (GLP-1) in the later postprandial phase.

Keywords: Gastric emptying; Glucagon-like peptide-1; Insulin; Insulin sensitivity; Postprandial blood glucose; Type 2 diabetes.

MeSH terms

  • Blood Glucose / analysis
  • Diabetes Mellitus, Type 2*
  • Gastric Emptying
  • Glucagon*
  • Humans
  • Insulin
  • Postprandial Period
  • Regression Analysis

Substances

  • Glucagon
  • Insulin
  • Blood Glucose