Abstract
Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure.
uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, N.I.H., Extramural
MeSH terms
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Insulin-Like Growth Factor Binding Proteins / metabolism
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Kinetics
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Matrix Metalloproteinase 2* / metabolism
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Methotrexate* / adverse effects
Substances
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Methotrexate
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Matrix Metalloproteinase 2
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Insulin-Like Growth Factor Binding Proteins