Temperature influence on NiFeMo nanoparticles magnetic properties and their viability in biomedical applications

J Biomed Mater Res B Appl Biomater. 2023 Aug;111(8):1488-1498. doi: 10.1002/jbm.b.35248. Epub 2023 Mar 7.

Abstract

NiFeMo alloy nanoparticles were synthesized by co-precipitation in the presence of organic additives. Nanoparticles thermal evolution shows that there is a significant increase in the average size (from 28 to 60 nm), consolidating a crystalline structure of the same type as the Ni3 Fe phase but with lattice parameter a = 0.362 nm. Measurements of magnetic properties follow this morphological and structural evolution increasing saturation magnetization (Ms) by 578% and reducing remanence magnetization (Mr) by 29%. Cell viability assays on as-synthesized revealed that nanoparticles (NPs) are not cytotoxic up to a concentration of 0.4 μg/mL for both non-tumorigenic (fibroblasts and macrophages) and tumor cells (melanoma).

Keywords: cell viability; co-precipitation; cytotoxicity; magnetic nanoparticles; organic additives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fibroblasts
  • Magnetic Phenomena
  • Magnetics
  • Nanoparticles* / chemistry
  • Temperature