Research on synthesis and property of nano-textured Sc2O3-MgO efficient antibacterial agents

J Biol Inorg Chem. 2023 Apr;28(3):329-343. doi: 10.1007/s00775-023-01995-2. Epub 2023 Mar 6.

Abstract

In order to obtain the inorganic efficient antibacterial agents, the means of ion doping and morphology construction in this research are used to enhance the antibacterial property of nano-MgO, which is according to the "oxidative damage mechanism" and "contact mechanism". In this work, the nano-textured Sc2O3-MgO are synthesized by doping Sc3+ in nano-MgO lattice through calcining at 600 °C. When the Sc3+ content reaches 10%, the nanotextures on the powders surface are pretty clearly visible and uniform, and the specific surface area and the oxygen vacancy are ideal, so that the 10% Sc3+-doped powders (SM-10) has the excellent antibacterial property against E. coli and S. aureus (MBC = 0.03 mg/mL). The efficient antibacterial agents in this research have a better antibacterial effect than the 0% Sc3+-doped powders (SM-0, MBC = 0.20 mg/mL) and the commercial nano-MgO (CM, MBC = 0.40 mg/mL), which have application prospects in the field of antibacterial.

Keywords: Antibacterial property; Ion doping; Nano-MgO; Nanotextures; Sc3+.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Escherichia coli
  • Nanoparticles* / chemistry
  • Oxygen
  • Staphylococcus aureus

Substances

  • Anti-Bacterial Agents
  • Oxygen