Synthesis of controlled-size starch nanoparticles and superparamagnetic starch nanocomposites by microemulsion method

Diana Morán; Gemma Gutiérrez; Rafael Mendoza; Marilyn Rayner; Carmen Blanco-López; María Matos

doi:10.1016/j.carbpol.2022.120223

Synthesis of controlled-size starch nanoparticles and superparamagnetic starch nanocomposites by microemulsion method

Carbohydr Polym. 2023 Jan 1:299:120223. doi: 10.1016/j.carbpol.2022.120223. Epub 2022 Oct 15.

Authors

Diana Morán¹, Gemma Gutiérrez¹, Rafael Mendoza², Marilyn Rayner³, Carmen Blanco-López⁴, María Matos⁵

Affiliations

¹ Department of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain; Instituto Universitario de Biotecnología de Asturias, University of Oviedo, 33006 Oviedo, Spain.
² Department of Physical and Analytical Chemistry, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain.
³ Department of Food Technology, Engineering, and Nutrition, Lund University, P.O. Box 124, SE 221 00 Lund, Sweden.
⁴ Instituto Universitario de Biotecnología de Asturias, University of Oviedo, 33006 Oviedo, Spain; Department of Physical and Analytical Chemistry, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain.
⁵ Department of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain; Instituto Universitario de Biotecnología de Asturias, University of Oviedo, 33006 Oviedo, Spain. Electronic address: matosmaria@uniovi.es.

PMID: 36876824
DOI: 10.1016/j.carbpol.2022.120223

Abstract

In this study, a synthesis process based on the microemulsion method (ME) was developed with the aim to produce controlled-size starch nanoparticles (SNPs). Several formulations were tested for the preparation of the W/O microemulsions varying the organic/aqueous phase ratios and co-stabilizers concentrations. SNPs were characterized in terms of size, morphology, monodispersity and crystallinity. Spherical shape particles with mean sizes 30-40 nm were prepared. The method was then used to simultaneously synthesize SNPs and iron oxide nanoparticles with superparamagnetic properties. Starch-based nanocomposites with superparamagnetic properties and controlled size were obtained. Therefore, the microemulsion method developed could be considered an innovative technology for the design and development of novel functional nanomaterials. The starch-based nanocomposites were evaluated in terms of morphology and magnetic properties, and they are being considered as promising sustainable nanomaterials for different biomedical applications.

Keywords: 1-Butanol (PubChem CID: 263); 1-Hexanol (PubChem CID: 8103); Absolute ethanol (PubChem CID: 702); Ammonia (PubChem CID: 222); CTAB (PubChem CID: 5974); Ferric chloride hexahydrate (PubChem CID: 16211236); Ferrous chloride tetrahydrate (PubChem CID: 16211588); Hydrochloric acid (PubChem CID: 313); Microemulsion; Nanocomposites; Size control; Sodium hydroxide (PubChem CID: 14798); Starch nanoparticles; Superparamagnetic particles; Urea (PubChem CID: 1176).