Pseudoclitoromegaly from acute T-cell lymphoblastic leukemia

Krista Birkemeier; Hale E Wills; Tesneem Issa; Amanda Farris; Joanna Stacey; Pamela Greene; Wajahat Dawood; Kurren Desai; Carrie Laborde; Bradley Trotter

doi:10.1080/08998280.2022.2139508

Pseudoclitoromegaly from acute T-cell lymphoblastic leukemia

Proc (Bayl Univ Med Cent). 2022 Nov 7;36(2):237-239. doi: 10.1080/08998280.2022.2139508. eCollection 2023.

Authors

Krista Birkemeier^{1

2}, Hale E Wills^{1

3}, Tesneem Issa^{1

4}, Amanda Farris^{1

4}, Joanna Stacey^{1

5}, Pamela Greene^{1

5}, Wajahat Dawood¹, Kurren Desai^{1

2}, Carrie Laborde^{1

4}, Bradley Trotter^{1

2}

Affiliations

¹ Texas A&M University Health Science Center, Temple, Texas.
² Department of Radiology, Baylor Scott & White McLane Children's Medical Center, Temple, Texas.
³ Department of Surgery, Baylor Scott & White McLane Children's Medical Center, Temple, Texas.
⁴ Department of Pediatrics, Baylor Scott & White McLane Children's Medical Center, Temple, Texas.
⁵ Department of Obstetrics and Gynecology, Baylor Scott & White McLane Children's Medical Center, Temple, Texas.

Abstract

A 7-year-old girl presented with painful genital enlargement, which was first believed to be clitoromegaly of hormonal origin. However, on the physical exam the clitoris was not visible and the prepuce and labia minora were enlarged and tender. Magnetic resonance imaging demonstrated an infiltrative abnormal signal with restricted diffusion involving the enlarged clitoris and adjacent soft tissues of the prepuce and labia minora, confirming a nonhormonal infiltrative malignancy. The same abnormal signal was present in enlarged inguinal lymph nodes, the kidneys, and an anterior mediastinal mass. The pathologic diagnosis was T-cell acute lymphoblastic leukemia.

Keywords: Clitoris; clitoromegaly; leukemia; magnetic resonance imaging; malignancy.

Publication types

Case Reports