A regressed germ cell tumor discovered secondary to azoospermia

Hiroki Tsujioka; Keiichiro Uemura; Toshiyuki Iwahata; Yasuyuki Inoue; Minoru Inoue; Akiyoshi Osaka; Akinori Nakayama; Hiroshi Okada; Kazutaka Saito

doi:10.1002/iju5.12552

A regressed germ cell tumor discovered secondary to azoospermia

IJU Case Rep. 2022 Nov 8;6(2):97-100. doi: 10.1002/iju5.12552. eCollection 2023 Mar.

Authors

Hiroki Tsujioka¹, Keiichiro Uemura^{1

2}, Toshiyuki Iwahata¹, Yasuyuki Inoue¹, Minoru Inoue¹, Akiyoshi Osaka¹, Akinori Nakayama¹, Hiroshi Okada¹, Kazutaka Saito¹

Affiliations

¹ Department of Urology Dokkyo Medical University Saitama Medical Center Koshigaya Saitama Japan.
² Department of Urology Kurume University Kurume Fukuoka Japan.

Abstract

Introduction: Regressed germ cell tumors are a rare disease commonly diagnosed with metastatic symptoms without local symptoms in the testis.

Case presentation: A 33-year-old man with azoospermia was referred to our hospital. His right testis was slightly swollen, and ultrasonography revealed hypoechogenicity of the right testis with decreased blood flow. Right high orchiectomy was performed. Pathologically, the seminiferous tubules were absent or highly atrophied with vitrification degeneration; however, no neoplastic lesion was confirmed. One-month post-surgery, the patient noticed a mass in the left supraclavicular fossa, of which a biopsy revealed seminoma. The patient was diagnosed with a regressed germ cell tumor and underwent systemic chemotherapy.

Conclusion: We reported the first case of a regressed germ cell tumor discovered due to complaints of azoospermia.

Keywords: azoospermia; regressed germ cell tumor; seminoma.

Publication types

Case Reports