Parathyroid Adenoma with a Pathological Fracture: A Rare Case Report

J Orthop Case Rep. 2022 Sep;12(9):37-40. doi: 10.13107/jocr.2022.v12.i09.3006.

Abstract

Introduction: Primary hyperparathyroidism may mimic osteoporosis and lead to pathological fractures.

Case report: We report a case of 35-year-old female who sustained left distal tibia-fibula fracture after a trivial fall, later diagnosed to have left inferior parathyroid adenoma. The fracture was managed conservatively and left inferior parathyroidectomy for the adenoma. At 4 years follow-up, there are no clinical or biochemical signs of recurrence.

Conclusion: Pathological fracture in a case of parathyroid adenoma is extremely rare and requires a multidisciplinary approach for optimal outcome. A combination of clinical, biological, radiological, and biochemical markers with a high index of suspicion in an isolated bone fracture is required to diagnose parathyroid adenoma.

Keywords: Pathological fracture; parathyroid adenoma; parathyroidectomy; single photon emission computed tomography; tibia-fibula fracture.

Publication types

  • Case Reports