[Research progress on chemical constituents of Schisandra chinensis and its effect on nonalcoholic fatty liver disease]

Zhongguo Zhong Yao Za Zhi. 2023 Feb;48(4):861-878. doi: 10.19540/j.cnki.cjcmm.20220616.201.
[Article in Chinese]

Abstract

Schisandra chinensis, a traditional Chinese medicinal herb, is rich in chemical constituents, including lignans, triterpenes, polysaccharides, and volatile oils. Clinically, it is commonly used to treat cardiovascular, cerebrovascular, liver, gastrointestinal, and respiratory diseases. Modern pharmacological studies have shown that S. chinensis extract and monomers have multiple pharmacological activities in lowering liver fat, alleviating insulin resistance, and resisting oxidative stress, and have good application prospects in alleviating nonalcoholic fatty liver disease(NAFLD). Therefore, this study reviewed the research progress on chemical constituents of S. chinensis and its effect on NAFLD in recent years to provide references for the research on S. chinensis in the treatment of NAFLD.

Keywords: Schisandra chinensis; chemical constituents; nonalcoholic fatty liver disease.

Publication types

  • English Abstract

MeSH terms

  • Insulin Resistance*
  • Lignans*
  • Non-alcoholic Fatty Liver Disease*
  • Schisandra*

Substances

  • Lignans