Pulmonary mucosa-associated lymphoid tissue lymphoma forming a reversed halo sign from ground-glass opacity

Ayano Watanabe; Koji Chihara; Masato Fujii; Kyoko Hijiya; Kazuya Iwai; Yuki Egawa; Yoshitaka Abe

doi:10.1016/j.radcr.2023.01.078

Pulmonary mucosa-associated lymphoid tissue lymphoma forming a reversed halo sign from ground-glass opacity

Radiol Case Rep. 2023 Feb 17;18(4):1633-1636. doi: 10.1016/j.radcr.2023.01.078. eCollection 2023 Apr.

Authors

Ayano Watanabe¹, Koji Chihara², Masato Fujii¹, Kyoko Hijiya², Kazuya Iwai³, Yuki Egawa⁴, Yoshitaka Abe⁵

Affiliations

¹ Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, 10-93, Ohte-machi, Aoi-ku, Shizuoka City, Shizuoka 420-8630, Japan.
² Department of Thoracic Surgery, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
³ Department of Hematology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
⁴ Department of Pathology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
⁵ Department of Diagnostic Radiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.

Abstract

The reversed halo sign (RHS) has been associated with various pulmonary diseases. We report a rare case of pulmonary mucosa-associated lymphoid tissue lymphoma forming a RHS from a ground-glass opacity (GGO). A 73-year-old man was followed-up for the GGO on his computed tomography images, which gradually extended peripherally. During the fourth year of follow-up, the GGO significantly evolved into a well-demarcated, oval lesion, with interlobular and intralobular septal thickenings, and multiple air spaces were surrounded by a well-defined thin consolidative rim, called the RHS. A pathologic study of the specimen via transbronchoscopic biopsy revealed pulmonary mucosa-associated lymphoid tissue lymphoma.

Keywords: Computed tomography; MALT lymphoma; Reversed halo.

Publication types

Case Reports